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Mx1 and Mx2 key antiviral proteins are surprisingly lost in toothed whales

Viral outbreaks in dolphins and other Delphinoidea family members warrant investigation into the integrity of the cetacean immune system. The dynamin-like GTPase genes Myxovirus 1 (Mx1) and Mx2 defend mammals against a broad range of viral infections. Loss of Mx1 function in human and mice enhances...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Braun, Benjamin A., Marcovitz, Amir, Camp, J. Gray, Jia, Robin, Bejerano, Gill
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491785/
https://ncbi.nlm.nih.gov/pubmed/26080416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501844112
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