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Mx1 and Mx2 key antiviral proteins are surprisingly lost in toothed whales
Viral outbreaks in dolphins and other Delphinoidea family members warrant investigation into the integrity of the cetacean immune system. The dynamin-like GTPase genes Myxovirus 1 (Mx1) and Mx2 defend mammals against a broad range of viral infections. Loss of Mx1 function in human and mice enhances...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491785/ https://ncbi.nlm.nih.gov/pubmed/26080416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501844112 |
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