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Mx1 and Mx2 key antiviral proteins are surprisingly lost in toothed whales

Viral outbreaks in dolphins and other Delphinoidea family members warrant investigation into the integrity of the cetacean immune system. The dynamin-like GTPase genes Myxovirus 1 (Mx1) and Mx2 defend mammals against a broad range of viral infections. Loss of Mx1 function in human and mice enhances...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Braun, Benjamin A., Marcovitz, Amir, Camp, J. Gray, Jia, Robin, Bejerano, Gill
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491785/
https://ncbi.nlm.nih.gov/pubmed/26080416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501844112
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