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Mapping fast protein folding with multiple-site fluorescent probes
Fast protein folding involves complex dynamics in many degrees of freedom, yet microsecond folding experiments provide only low-resolution structural information. We enhance the structural resolution of the five-helix bundle protein λ(6–85) by engineering into it three fluorescent tryptophan–tyrosin...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491763/ https://ncbi.nlm.nih.gov/pubmed/26080403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422683112 |
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