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The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells
The molecular chaperone HSP90 is involved in stabilization and function of multiple client proteins, many of which represent important oncogenic drivers in NSCLC. Utilization of HSP90 inhibitors as radiosensitizing agents is a promising approach. The antitumor activity of ganetespib, HSP90 inhibitor...
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| Publicado en: | Cancers (Basel) |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491689/ https://ncbi.nlm.nih.gov/pubmed/26010604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7020814 |
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