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Mechanisms of Acquired Resistance to ALK Inhibitors and the Rationale for Treating ALK-positive Lung Cancer

The discovery of an echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion gene led to improved clinical outcomes in patients with lung cancer after the development of the first ALK-targeting agent, crizotinib. Some second-generation ALK tyrosine kinase inhib...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancers (Basel)
मुख्य लेखकों: Isozaki, Hideko, Takigawa, Nagio, Kiura, Katsuyuki
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491683/
https://ncbi.nlm.nih.gov/pubmed/25941796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7020763
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