Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogaster

The compounds 4-vinylcyclohexene 1,2-monoepoxide (VCM) and 4-Vinylcyclohexene diepoxide (VCD) are the two downstream metabolites of 4-vinylcyclohexene (VCH), an ovotoxic agent in mammals. In addition, VCM and VCD may be found as by-products of VCH oxidation in the environment. Recently, we reported...

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Publicado en:Redox Biol
Autores principales: Abolaji, Amos O., Kamdem, Jean P., Lugokenski, Thiago H., Farombi, Ebenezer O., Souza, Diogo O., da Silva Loreto, Élgion L., Rocha, João B.T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491645/
https://ncbi.nlm.nih.gov/pubmed/26117601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.06.001
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