Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome

Nitrite is a storage reservoir of nitric oxide that is readily reduced to nitric oxide under pathological conditions. Previous studies have demonstrated that nitrite levels are significantly reduced in cardiovascular disease states, including peripheral vascular disease. We investigated the cytoprot...

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Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Polhemus, David J., Bradley, Jessica M., Islam, Kazi N., Brewster, Luke P., Calvert, John W., Tao, Ya-Xiong, Chang, Carlos C., Pipinos, Iraklis I., Goodchild, Traci T., Lefer, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Vascular Biology and Microcirculation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491519/
https://ncbi.nlm.nih.gov/pubmed/25910804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00115.2015
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