Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome

Nitrite is a storage reservoir of nitric oxide that is readily reduced to nitric oxide under pathological conditions. Previous studies have demonstrated that nitrite levels are significantly reduced in cardiovascular disease states, including peripheral vascular disease. We investigated the cytoprot...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Polhemus, David J., Bradley, Jessica M., Islam, Kazi N., Brewster, Luke P., Calvert, John W., Tao, Ya-Xiong, Chang, Carlos C., Pipinos, Iraklis I., Goodchild, Traci T., Lefer, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491519/
https://ncbi.nlm.nih.gov/pubmed/25910804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00115.2015
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