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Plasma gelsolin improves lung host defense against pneumonia by enhancing macrophage NOS3 function

Plasma gelsolin (pGSN) functions as part of the “extracellular actin-scavenging system,” but its potential to improve host defense against infection has not been studied. In a mouse model of primary pneumococcal pneumonia, recombinant human pGSN (rhu-pGSN) caused enhanced bacterial clearance, reduce...

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Bibliografiset tiedot
Julkaisussa:Am J Physiol Lung Cell Mol Physiol
Päätekijät: Yang, Zhiping, Chiou, Terry Ting-Yu, Stossel, Thomas P., Kobzik, Lester
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491512/
https://ncbi.nlm.nih.gov/pubmed/25957291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00094.2015
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