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Accelerated extracellular matrix turnover during exacerbations of COPD

BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) contribute significantly to disease progression. However, the effect on tissue structure and turnover is not well described. There is an urgent clinical need for biomarkers of disease activity associated with disease progressi...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Sand, Jannie M. B., Knox, Alan J., Lange, Peter, Sun, Shu, Kristensen, Jacob H., Leeming, Diana J., Karsdal, Morten A., Bolton, Charlotte E., Johnson, Simon R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491243/
https://ncbi.nlm.nih.gov/pubmed/26062683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0225-3
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