Thrombin Down-Regulates Tissue Factor Pathway Inhibitor Expression in a PI3K/Nuclear Factor-κB–Dependent Manner in Human Pleural Mesothelial Cells

Tissue factor pathway inhibitor (TFPI) is the primary inhibitor of the extrinsic coagulation cascade, and its expression is reported to be relatively stable. Various pathophysiologic agents have been shown to influence TFPI activity by regulating its expression or by modifying the protein. It is not...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Jeffers, Ann, Owens, Shuzi, Koenig, Kathleen, Quaid, Brandon, Pendurthi, Usha R., Rao, Vijaya M., Idell, Steven, Tucker, Torry A.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491127/
https://ncbi.nlm.nih.gov/pubmed/25303460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0084OC
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