Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer

A large number of DNA copy number alterations (CNAs) exist in human breast cancers, and thus characterizing the most frequent CNAs is key to advancing therapeutics because it is likely that these regions contain breast tumor ‘drivers’ (i.e., cancer causal genes). This study aims to characterize the...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Silva, Grace O., He, Xiaping, Parker, Joel S., Gatza, Michael L., Carey, Lisa A., Hou, Jack P., Moulder, Stacy L., Marcom, Paul K., Ma, Jian, Rosen, Jeffrey M., Perou, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Preclinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491106/
https://ncbi.nlm.nih.gov/pubmed/26109346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3476-2
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