Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer

A large number of DNA copy number alterations (CNAs) exist in human breast cancers, and thus characterizing the most frequent CNAs is key to advancing therapeutics because it is likely that these regions contain breast tumor ‘drivers’ (i.e., cancer causal genes). This study aims to characterize the...

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Bibliografski detalji
Izdano u:Breast Cancer Res Treat
Glavni autori: Silva, Grace O., He, Xiaping, Parker, Joel S., Gatza, Michael L., Carey, Lisa A., Hou, Jack P., Moulder, Stacy L., Marcom, Paul K., Ma, Jian, Rosen, Jeffrey M., Perou, Charles M.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2015
Teme:
Preclinical Study
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491106/
https://ncbi.nlm.nih.gov/pubmed/26109346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3476-2
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