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Eliminate mitochondrial diseases by gene editing in germ-line cells and embryos

Nuclease-based gene editing technologies have opened up opportunities for correcting human genetic diseases. For the first time, scientists achieved targeted gene editing of mitochondrial DNA in mouse oocytes fused with patient cells. This fascinating progression may encourage the development of nov...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Protein Cell
Hauptverfasser: Wang, Si, Yi, Fei, Qu, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Higher Education Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491053/
https://ncbi.nlm.nih.gov/pubmed/26081469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0177-x
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