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Eliminate mitochondrial diseases by gene editing in germ-line cells and embryos

Nuclease-based gene editing technologies have opened up opportunities for correcting human genetic diseases. For the first time, scientists achieved targeted gene editing of mitochondrial DNA in mouse oocytes fused with patient cells. This fascinating progression may encourage the development of nov...

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Bibliografiske detaljer
Udgivet i:Protein Cell
Main Authors: Wang, Si, Yi, Fei, Qu, Jing
Format: Artigo
Sprog:Inglês
Udgivet: Higher Education Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491053/
https://ncbi.nlm.nih.gov/pubmed/26081469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0177-x
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