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PD-1 regulates imiquimod-induced psoriasiform dermatitis through inhibition of IL-17A expression by innate γδ low T Cells
Programmed cell death 1 (PD-1) is key regulatory molecule that has been targeted in human cancers, including melanoma. In clinical testing, antibodies against PD-1 have resulted in psoriasiform dermatitis (PsD). To determine if PD-1 regulates PsD, we compared skin responses of PD-1-deficient (PD-1KO...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490979/ https://ncbi.nlm.nih.gov/pubmed/26048148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500448 |
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