Doxorubicin Resistance in Breast Cancer is Driven by Light at Night Induced Disruption of the Circadian Melatonin Signal

Chemotherapeutic resistance, particularly to doxorubicin (Dox), represents a major impediment to successfully treating breast cancer and is linked to elevated tumor metabolism and tumor over-expression and/or activation of various families of receptor- and non-receptor-associated tyrosine kinases. D...

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Pubblicato in:J Pineal Res
Autori principali: Xiang, Shulin, Dauchy, Robert T., Hauch, Adam, Mao, Lulu, Yuan, Lin, Wren, Melissa A., Belancio, Victoria P., Mondal, Debasis, Frasch, Tripp, Blask, David E., Hill, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490975/
https://ncbi.nlm.nih.gov/pubmed/25857269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12239
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