Detection of BCR-ABL T315I mutation by peptide nucleic acid directed PCR clamping and by peptide nucleic acid FISH

BACKGROUND: Mutations of the BCR-ABL1 fusion gene represent a well established cause of resistance to tyrosine kinase inhibitors. Among the different mutations identified T315I is of particular concern since it is not effectively targeted by the majority of Tyrosine Kinase Inhibitors so far availabl...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biomark Res
Päätekijät: Rosso, Valentina, Bracco, Enrico, Pedrola, Roberto, Carturan, Sonia, Signorino, Elisabetta, Petiti, Jessica, Calabrese, Chiara, Nicoli, Paolo, De Gobbi, Marco, Gaidano, Valentina, Gallo, Daniela, Ulisciani, Stefano, Fava, Carmen, Rege-Cambrin, Giovanna, Frassoni, Francesco, Saglio, Giuseppe, Cilloni, Daniela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Methodology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490729/
https://ncbi.nlm.nih.gov/pubmed/26146560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-015-0039-y
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