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Chronic morphine and HIV-1 Tat promote differential central nervous system trafficking of CD3+ and Ly6C+ immune cells in a murine Streptococcus pneumoniae infection model

BACKGROUND: Persistent systemic infection results in excessive trafficking of peripheral immune cells into the central nervous system (CNS), thereby contributing to sustained neuroinflammation that leads to neurocognitive deficits. In this study, we explored the role of opportunistic systemic infect...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Dutta, Raini, Roy, Sabita
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490693/
https://ncbi.nlm.nih.gov/pubmed/26087960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0341-5
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