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Chronic morphine and HIV-1 Tat promote differential central nervous system trafficking of CD3+ and Ly6C+ immune cells in a murine Streptococcus pneumoniae infection model

BACKGROUND: Persistent systemic infection results in excessive trafficking of peripheral immune cells into the central nervous system (CNS), thereby contributing to sustained neuroinflammation that leads to neurocognitive deficits. In this study, we explored the role of opportunistic systemic infect...

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Библиографические подробности
Опубликовано в: :J Neuroinflammation
Главные авторы: Dutta, Raini, Roy, Sabita
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490693/
https://ncbi.nlm.nih.gov/pubmed/26087960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0341-5
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