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Cu(II) enhances the effect of Alzheimer’s amyloid-β peptide on microglial activation
BACKGROUND: Aggregated forms of amyloid-β (Aβ) peptides are important triggers for microglial activation, which is an important pathological component in the brains of Alzheimer’s patients. Cu(II) ions are reported to be coordinated to monomeric Aβ, drive Aβ aggregation, and potentiate Aβ neurotoxic...
Guardat en:
| Publicat a: | J Neuroinflammation |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490619/ https://ncbi.nlm.nih.gov/pubmed/26104799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0343-3 |
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