Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1

The apolipoprotein L1 (APOL1) gene (APOL1) product is toxic to kidney cells, and its G1 and G2 alleles are strongly associated with increased risk for kidney disease progression in African Americans. Variable penetrance of the G1 and G2 risk alleles highlights the significance of additional factors...

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Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Cell Physiol
Egile Nagusiak: Khatua, Atanu K., Cheatham, Amber M., Kruzel, Etty D., Singhal, Pravin C., Skorecki, Karl, Popik, Waldemar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2015
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490327/
https://ncbi.nlm.nih.gov/pubmed/25924622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00384.2014
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