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Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells

Head and neck squamous cell carcinoma (HNSCC) is a major killer worldwide and innovative measures are urgently warranted to lower the morbidity and mortality caused by this malignancy. Aberrant redox and metabolic status in HNSCC cells offer a unique opportunity to specifically target cancer cells....

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Shrotriya, Sangeeta, Deep, Gagan, Lopert, Pamela, Patel, Manisha, Agarwal, Rajesh, Agarwal, Chapla
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490158/
https://ncbi.nlm.nih.gov/pubmed/25557495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22246
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