Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G(2)/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells

Head and neck squamous cell carcinoma (HNSCC) accounts for 6% of all malignancies in USA and unfortunately the recurrence of secondary primary tumors and resistance against conventional treatments decrease the overall 5 year survival rate in HNSCC patients. Thus, additional approaches are needed to...

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Detalhes bibliográficos
Main Authors: Shrotriya, Sangeeta, Deep, Gagan, Gu, Mallikarjuna, Kaur, Manjinder, Jain, Anil K., Inturi, Swetha, Agarwal, Rajesh, Agarwal, Chapla
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Inflammation, Microenvironment and Prevention
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324440/
https://ncbi.nlm.nih.gov/pubmed/22266465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs019
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