Leukemia cell mobilization with G-CSF plus plerixafor during busulfan-fludarabine conditioning in allogeneic stem cell transplantation

We hypothesized that during conditioning chemotherapy for allogeneic stem cell transplant (allo-SCT), disruption of stromal-leukemia interactions using granulocyte-colony stimulating factor (G-CSF) in combination with the CXCR4-specific inhibitor plerixafor, may promote release of leukemic cells fro...

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Veröffentlicht in:Bone Marrow Transplant
Hauptverfasser: Konopleva, Marina, Benton, Christopher B., Thall, Peter F., Zeng, Zhihong, Shpall, Elizabeth, Ciurea, Stefan, Kebriaei, Partow, Alousi, Amin, Popat, Uday, Anderlini, Paolo, Nieto, Yago, Parmar, Simrit, Qiao, Wei, Chen, Julianne, Rondon, Gabriela, McMullin, Becky, Wang, Rui-Yu, Lu, Hongbo, Schober, Wendy, Woodworth, Glenda, Gulbis, Alison, Cool, Rita, Andreeff, Michael, Champlin, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490031/
https://ncbi.nlm.nih.gov/pubmed/25867648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2015.58
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