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Whole-Exome Enrichment with the Roche NimbleGen SeqCap EZ Exome Library SR Platform

Multiple platforms are available for whole-exome enrichment and sequencing (WES). This protocol is based on the Roche NimbleGen SeqCap EZ Exome Library SR platform, which enriches for ~44 Mb of the human exonic regions. The SeqCap system uses 55- to 105-base DNA probes to capture known coding DNA se...

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Dettagli Bibliografici
Pubblicato in:Cold Spring Harb Protoc
Autori principali: Chen, Rui, Im, Hogune, Snyder, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490009/
https://ncbi.nlm.nih.gov/pubmed/25762419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.prot084855
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