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Whole-Exome Enrichment with the Roche NimbleGen SeqCap EZ Exome Library SR Platform

Multiple platforms are available for whole-exome enrichment and sequencing (WES). This protocol is based on the Roche NimbleGen SeqCap EZ Exome Library SR platform, which enriches for ~44 Mb of the human exonic regions. The SeqCap system uses 55- to 105-base DNA probes to capture known coding DNA se...

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Detalles Bibliográficos
Publicado en:Cold Spring Harb Protoc
Main Authors: Chen, Rui, Im, Hogune, Snyder, Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490009/
https://ncbi.nlm.nih.gov/pubmed/25762419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.prot084855
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