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WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis Through an Actin Comet Tail Mechanism

Nucleation promoting factors (NPFs) control the spatio-temporal activity of Arp2/3 complex in cells [1, 2]. Thus, WASP and the WAVE complex direct the formation of branched actin networks at the leading edge during cell motility and endo/exocytosis, whereas the WASH complex is involved in endosomal...

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Bibliografiske detaljer
Udgivet i:Curr Biol
Main Authors: Kast, David J., Zajac, Allison L., Holzbaur, Erika L.F., Ostap, E. Michael, Dominguez, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489997/
https://ncbi.nlm.nih.gov/pubmed/26096974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.05.042
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