Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

The human cerebral cortex develops through an elaborate succession of cellular events that, when disrupted, can lead to neuropsychiatric disease. The ability to reprogram somatic cells into pluripotent cells that can be differentiated in vitro provides a unique opportunity to study normal and abnorm...

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Udgivet i:Nat Methods
Main Authors: Paşca, Anca M, Sloan, Steven A, Clarke, Laura E, Tian, Yuan, Makinson, Christopher D, Huber, Nina, Kim, Chul Hoon, Park, Jin-Young, O’Rourke, Nancy A, Nguyen, Khoa D, Smith, Stephen J, Huguenard, John R, Geschwind, Daniel H, Barres, Ben A, Paşca, Sergiu P
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489980/
https://ncbi.nlm.nih.gov/pubmed/26005811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3415
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