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Extending the lifespan and efficacies of immune cells used in adoptive transfer for cancer immunotherapies–A review

Cells used in adoptive cell-transfer immunotherapies against cancer include dendritic cells (DCs), natural-killer cells, and CD8(+) T-cells. These cells may have limited efficacy due to their lifespan, activity, and immunosuppressive effects of tumor cells. Therefore, increasing longevity and activi...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Nayar, Sandeep, Dasgupta, Prokar, Galustian, Christine
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489929/
https://ncbi.nlm.nih.gov/pubmed/26155387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.1002720
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