Targeting Prostate Cancer Using Intratumoral Cytotopically Modified Interleukin-15 Immunotherapy in a Syngeneic Murine Model

BACKGROUND: The prostate cancer microenvironment is highly immunosuppressive; immune cells stimulated in the periphery by systemic immunotherapies will be rendered inactive once entering this environment. Immunotherapies for prostate cancer need to break this immune tolerance. We have previously ide...

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Detalhes bibliográficos
Publicado no:Immunotargets Ther
Main Authors: Papaevangelou, Efthymia, Smolarek, Dorota, Smith, Richard A, Dasgupta, Prokar, Galustian, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394845/
https://ncbi.nlm.nih.gov/pubmed/32802803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S257443
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