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Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease affecting spinal cord motoneurons (MN) with an associative connection to Frontotemporal Lobar Dementia (FTLD). The endoplasmic reticulum (ER) bound Sigma-1 Receptor (S1R) chaperone protein localizes to specialized ER cisternae within...

詳細記述

保存先:
書誌詳細
出版年:J Pharmacol Sci
主要な著者: Mavlyutov, Timur A., Guo, Lian-Wang, Epstein, Miles L., Ruoho, Arnold E.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489701/
https://ncbi.nlm.nih.gov/pubmed/25704013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jphs.2014.12.013
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