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LACK OF SIGMA-1 RECEPTOR EXACERBATES ALS PROGRESSION IN MICE

The function of the sigma-1 receptor (S1R) has been implicated in modulating the activity of various ion channels. In the Central Nervous System (CNS) S1R is enriched in cholinergic postsynaptic densities in spinal cord motoneurons (MN). Mutations in S1R have been found in familial cases of Amyotrop...

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書誌詳細
主要な著者: Mavlyutov, Timur A., Epstein, Miles L., Verbny, Yakov I., Huerta, Maria S., Zaitoun, Ismail, Ziskind-Conhaim, Lea, Ruoho, Arnold E.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665351/
https://ncbi.nlm.nih.gov/pubmed/23458708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.02.035
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