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Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase.

Mitogenic signals initiated at the plasma membrane by extracellular factors acting on receptor tyrosine kinases or G protein-coupled receptors are transmitted to the nucleus through an intricate signaling network. Components of this network participate, upon stimulation, in a complex array of phosph...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Patriotis, C, Makris, A, Chernoff, J, Tsichlis, P N
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1994
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937886/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.9755
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