Pulmonary Macrophages Attenuate Hypoxic Pulmonary Vasoconstriction via β(3)AR/iNOS Pathway in Rats Exposed to Chronic Intermittent Hypoxia

Chronic intermittent hypoxia (IH) induces activation of the sympathoadrenal system, which plays a pivotal role in attenuating hypoxic pulmonary vasoconstriction (HPV) via central β(1)-adrenergic receptors (AR) (brain) and peripheral β(2)AR (pulmonary arteries). Prolonged hypercatecholemia has been s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nagai, Hisashi, Kuwahira, Ichiro, Schwenke, Daryl O., Tsuchimochi, Hirotsugu, Nara, Akina, Ogura, Sayoko, Sonobe, Takashi, Inagaki, Tadakatsu, Fujii, Yutaka, Yamaguchi, Rutsuko, Wingenfeld, Lisa, Umetani, Keiji, Shimosawa, Tatsuo, Yoshida, Ken-ichi, Uemura, Koichi, Pearson, James T., Shirai, Mikiyasu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489089/
https://ncbi.nlm.nih.gov/pubmed/26132492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131923
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