β(2)-Adrenergic Receptor-Dependent Attenuation of Hypoxic Pulmonary Vasoconstriction Prevents Progression of Pulmonary Arterial Hypertension in Intermittent Hypoxic Rats

In sleep apnea syndrome (SAS), intermittent hypoxia (IH) induces repeated episodes of hypoxic pulmonary vasoconstriction (HPV) during sleep, which presumably contribute to pulmonary arterial hypertension (PAH). However, the prevalence of PAH was low and severity is mostly mild in SAS patients, and m...

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Detalhes bibliográficos
Main Authors: Nagai, Hisashi, Kuwahira, Ichiro, Schwenke, Daryl O., Tsuchimochi, Hirotsugu, Nara, Akina, Inagaki, Tadakatsu, Ogura, Sayoko, Fujii, Yutaka, Umetani, Keiji, Shimosawa, Tatsuo, Yoshida, Ken-ichi, Pearson, James T., Uemura, Koichi, Shirai, Mikiyasu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211686/
https://ncbi.nlm.nih.gov/pubmed/25350545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110693
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