Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption

The Nicotine Metabolite Ratio (NMR, ratio of trans-3’-hydroxycotinine and cotinine), has previously been associated with CYP2A6 activity, response to smoking cessation treatments, and cigarette consumption. We searched for drug metabolizing enzyme and transporter (DMET) gene variation associated wit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bergen, Andrew W., Michel, Martha, Nishita, Denise, Krasnow, Ruth, Javitz, Harold S., Conneely, Karen N., Lessov-Schlaggar, Christina N., Hops, Hyman, Zhu, Andy Z. X., Baurley, James W., McClure, Jennifer B., Hall, Sharon M., Baker, Timothy B., Conti, David V., Benowitz, Neal L., Lerman, Caryn, Tyndale, Rachel F., Swan, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488893/
https://ncbi.nlm.nih.gov/pubmed/26132489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126113
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