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Identification of novel CYP2A6*1B variants; the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism

BACKGROUND: Cytochrome P450 2A6 (CYP2A6) is the human enzyme responsible for the majority of nicotine’s metabolism. CYP2A6 genetic variants contribute to the inter-individual and inter-ethnic variation in nicotine metabolism. We examined the association between the CYP2A6*1B variant and nicotine’s i...

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Detalhes bibliográficos
Main Authors: Mwenifumbo, Jill C., Lessov-Schlaggar, Christina N., Zhou, Qian, Krasnow, Ruth E., Swan, Gary E., Benowitz, Neal L., Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921956/
https://ncbi.nlm.nih.gov/pubmed/17522595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.clpt.6100246
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