miR-203 Inhibits Frizzled-2 Expression via CD82/KAI1 Expression in Human Lung Carcinoma Cells

CD82/KAI1, a member of the tetraspanin superfamily, is a suppressor of metastasis and CD82 inhibits canonical Wnt signaling via downregulation of several Frizzled (FZD) isoforms, resulting in accumulation of β-catenin at the cell membrane. In this study, we investigated the mechanism through which C...

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Udgivet i:PLoS One
Main Authors: Mine, Mariko, Yamaguchi, Kojiro, Sugiura, Tsuyoshi, Chigita, Satomi, Yoshihama, Naoya, Yoshihama, Rumi, Hiyake, Naomi, Kobayashi, Yosuke, Mori, Yoshihide
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488846/
https://ncbi.nlm.nih.gov/pubmed/26132195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131350
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