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A Novel Function of CD82/KAI1 in Sialyl Lewis Antigen-Mediated Adhesion of Cancer Cells: Evidence for an Anti-Metastasis Effect by Down-Regulation of Sialyl Lewis Antigens

We have recently elucidated a novel function for CD82 in E-cadherin-mediated homocellular adhesion; due to this function, it can inhibit cancer cell dissociation from the primary cancer nest and limit metastasis. However, the effect of CD82 on selectin ligand-mediated heterocellular adhesion has not...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yoshihama, Naoya, Yamaguchi, Koujiro, Chigita, Satomi, Mine, Mariko, Abe, Masakazu, Ishii, Kotaro, Kobayashi, Yosuke, Akimoto, Naonari, Mori, Yoshihide, Sugiura, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414583/
https://ncbi.nlm.nih.gov/pubmed/25923697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124743
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