From mouse to man: safety, immunogenicity and efficacy of a candidate leishmaniasis vaccine LEISH-F3+GLA-SE

Key antigens of Leishmania species identified in the context of host responses in Leishmania-exposed individuals from disease-endemic areas were prioritized for the development of a subunit vaccine against visceral leishmaniasis (VL), the most deadly form of leishmaniasis. Two Leishmania proteins—nu...

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Veröffentlicht in:Clin Transl Immunology
Hauptverfasser: Coler, Rhea N, Duthie, Malcolm S, Hofmeyer, Kimberly A, Guderian, Jeffery, Jayashankar, Lakshmi, Vergara, Julie, Rolf, Tom, Misquith, Ayesha, Laurance, John D, Raman, Vanitha S, Bailor, H Remy, Cauwelaert, Natasha Dubois, Reed, Steven J, Vallur, Aarthy, Favila, Michelle, Orr, Mark T, Ashman, Jill, Ghosh, Prakash, Mondal, Dinesh, Reed, Steven G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488838/
https://ncbi.nlm.nih.gov/pubmed/26175894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2015.6
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