NF-κBp65 and Expression of Its Pro-Inflammatory Target Genes Are Upregulated in the Subcutaneous Adipose Tissue of Cachectic Cancer Patients

Cancer cachexia, of which the most notable symptom is severe and rapid weight loss, is present in the majority of patients with advanced cancer. Inflammatory mediators play an important role in the development of cachexia, envisaged as a chronic inflammatory syndrome. The white adipose tissue (WAT)...

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Veröffentlicht in:Nutrients
Hauptverfasser: Gonzalez Camargo, Rodolfo, Mendes dos Reis Riccardi, Daniela, Quintas Teixeira Ribeiro, Henrique, Carlos Carnevali, Luiz, Marques de Matos-Neto, Emidio, Enjiu, Lucas, Xavier Neves, Rodrigo, Darck Carola Correia Lima, Joanna, Galvão Figuerêdo, Raquel, Sérgio Martins de Alcântara, Paulo, Maximiano, Linda, Otoch, José, Batista, Miguel Luiz, Püschel, Gerhard, Seelaender, Marilia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488796/
https://ncbi.nlm.nih.gov/pubmed/26053616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu7064465
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