Ribozyme-mediated suppression of Moloney murine leukemia virus and human immunodeficiency virus type I replication in permissive cell lines.

Several hammerhead ribozymes targeted to different sites within the retroviral packaging (psi) sequences of the Moloney murine leukemia virus (Mo-MLV) and the human immunodeficiency virus type 1 (HIV-1) were designed and shown to cleave target RNA in vitro at the chosen sites. The engineered ribozym...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Sun, L Q, Warrilow, D, Wang, L, Witherington, C, Macpherson, J, Symonds, G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.9715
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