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Defects in Virion Production Caused by Mutations Affecting the C-Terminal Portion of the Moloney Murine Leukemia Virus Capsid Protein
The capsid (CA) domain of the Moloney murine leukemia virus (Mo-MuLV) Gag protein has a unique carboxy terminus with a highly charged arginine-rich sequence. Mutant viruses harboring arginine-to-alanine mutations affecting this region of CA displayed significant defects in virion release, and the fe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149736/ https://ncbi.nlm.nih.gov/pubmed/12584360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.3339-3344.2003 |
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