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Defects in Virion Production Caused by Mutations Affecting the C-Terminal Portion of the Moloney Murine Leukemia Virus Capsid Protein

The capsid (CA) domain of the Moloney murine leukemia virus (Mo-MuLV) Gag protein has a unique carboxy terminus with a highly charged arginine-rich sequence. Mutant viruses harboring arginine-to-alanine mutations affecting this region of CA displayed significant defects in virion release, and the fe...

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Hlavní autoři: Wang, Margaret Q., Goff, Stephen P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC149736/
https://ncbi.nlm.nih.gov/pubmed/12584360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.5.3339-3344.2003
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