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JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex Traits

Gene-set analysis has been proposed as a powerful tool to deal with the highly polygenic architecture of complex traits, as well as with the small effect sizes typically found in GWAS studies for complex traits. We developed a tool, Joint Association of Genetic variants (JAG), which can be applied t...

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Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Lips, Esther S., Kooyman, Maarten, de Leeuw, Christiaan, Posthuma, Danielle
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488663/
https://ncbi.nlm.nih.gov/pubmed/26110313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes6020238
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