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Genetic mapping of cell type specificity for complex traits

Single-cell RNA sequencing (scRNA-seq) data allows to create cell type specific transcriptome profiles. Such profiles can be aligned with genome-wide association studies (GWASs) to implicate cell type specificity of the traits. Current methods typically rely only on a small subset of available scRNA...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Watanabe, Kyoko, Umićević Mirkov, Maša, de Leeuw, Christiaan A., van den Heuvel, Martijn P., Posthuma, Danielle
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642112/
https://ncbi.nlm.nih.gov/pubmed/31324783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11181-1
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