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EMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer Progression

DNA mismatch repair (MMR) function is critical for correcting errors coincident with polymerase-driven DNA replication, and its proteins are frequent targets for inactivation (germline or somatic), generating a hypermutable tumor that drives cancer progression. The biomarker for defective DNA MMR is...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Carethers, John M., Koi, Minoru, Tseng-Rogenski, Stephanie S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488660/
https://ncbi.nlm.nih.gov/pubmed/25836926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes6020185
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