Hormonal status and age differentially affect tolerance to the disruptive effects of delta-9-tetrahydrocannabinol (Δ(9)-THC) on learning in female rats

The effects of hormone status and age on the development of tolerance to Δ(9)-THC were assessed in sham-operated (intact) or ovariectomized (OVX) female rats that received either intraperitoneal saline or 5.6 mg/kg of Δ(9)-THC daily from postnatal day (PD) 75–180 (early adulthood onward) or PD 35–14...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Winsauer, Peter J., Filipeanu, Catalin M., Weed, Peter F., Sutton, Jessie L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2015
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488627/
https://ncbi.nlm.nih.gov/pubmed/26191005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00133
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