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Tolerance to hypothermic and antinoceptive effects of Δ9-tetrahydrocannabinol (THC) vapor inhalation in rats

RATIONALE: A reduced effect of a given dose of Δ(9)-tetrahydrocannabinol (THC) emerges with repeated exposure to the drug. This tolerance can vary depending on THC dose, exposure chronicity and the behavioral or physiological measure of interest. A novel THC inhalation system based on e-cigarette te...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Nguyen, Jacques D., Grant, Yanabel, Kerr, Tony M., Gutierrez, Arnold, Cole, Maury, Taffe, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6713267/
https://ncbi.nlm.nih.gov/pubmed/30031028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2018.07.007
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