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An Efficient Method for Identifying Gene Fusions by Targeted RNA Sequencing from Fresh Frozen and FFPE Samples

Fusion genes are known to be key drivers of tumor growth in several types of cancer. Traditionally, detecting fusion genes has been a difficult task based on fluorescent in situ hybridization to detect chromosomal abnormalities. More recently, RNA sequencing has enabled an increased pace of fusion g...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Scolnick, Jonathan A., Dimon, Michelle, Wang, I-Ching, Huelga, Stephanie C., Amorese, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488430/
https://ncbi.nlm.nih.gov/pubmed/26132974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128916
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